Larazotide

Larazotide — also known as AT-1001 — is a synthetic octapeptide studied for its potential ability to regulate intestinal tight junctions. Research explores how Larazotide may influence gut barrier integrity, permeability, and inflammatory signaling pathways in preclinical and clinical models. It is often investigated in the context of gastrointestinal health, including conditions involving increased intestinal permeability (“leaky gut”), but it is not FDA-approved for general medical use.